The Matrice 4 series comes with an integrated DJI RTK module which supports the extended L5 frequency band and features GNSS+Vision Fusion Positioning and Navigation System. It allows for the return-to-home point to be updated through visual positioning, allowing for rapid takeoff within 15 seconds. Even without GNSS signals, it can complete the return-to-home process, effectively overcoming signal obstructions and interference commonly found in urban environments.

When operating during the day or night in urban regions, the remote controller can display the names of buildings and landmarks in real-time, marking core roads with prominent lines.

Matrice 400 has a built-in video transmission relay module. With this setup, one Matrice 400 can serve as a relay drone, flying high to provide relay signals for another Matrice 400 operating at a greater distance. This capability significantly extends the transmission range, making it ideal for search and rescue tasks as well as inspections in mountainous areas.